• Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility 

      Meulenbelt, I.; Bos, S. D.; Chapman, K.; van der Breggen, R.; Houwing-Duistermaat, J. J.; Kremer, D.; Kloppenburg, M.; Carr, A.; Tsezou, A.; Gonzalez, A.; Loughlin, J.; Slagboom, E. (2011)
      Objective To study whether common genetic variants of the genes involved in the complex regulatory mechanism determining the intracellular bio-availability of T3 influence osteoarthritis onset. Methods In total 17 genetic ...
    • Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22 

      Evangelou, E.; Valdes, A. M.; Kerkhof, H. J. M.; Styrkarsdottir, U.; Zhu, Y.; Meulenbelt, I.; Lories, R. J.; Karassa, F. B.; Tylzanowski, P.; Bos, S. D.; Rayner, N. W.; Southam, L.; Zhai, G.; Elliott, K. S.; Hunt, S. E.; Blackburn, H.; Potter, S. C.; Day-Williams, A. G.; Beazley, C.; Akune, T.; Arden, N. K.; Carr, A.; Chapman, K.; Cupples, L. A.; Dai, J.; Deloukas, P.; Doherty, M.; Doherty, S.; Engstrom, G.; Gonzalez, A.; Halldorsson, B. V.; Hammond, C. L.; Hart, D. J.; Helgadottir, H.; Hofman, A.; Ikegawa, S.; Ingvarsson, T.; Jiang, Q.; Jonsson, H.; Kaprio, J.; Kawaguchi, H.; Kisand, K.; Kloppenburg, M.; Kujala, U. M.; Lohmander, L. S.; Loughlin, J.; Luyten, F. P.; Mabuchi, A.; McCaskie, A.; Nakajima, M.; Nilsson, P. M.; Nishida, N.; Ollier, W. E. R.; Panoutsopoulou, K.; Van De Putte, T.; Ralston, S. H.; Rivadeneira, F.; Saarela, J.; Schulte-Merker, S.; Shi, D.; Slagboom, P. E.; Sudo, A.; Tamm, A.; Thorleifsson, G.; Thorsteinsdottir, U.; Tsezou, A.; Wallis, G. A.; Wilkinson, J. M.; Yoshimura, N.; Zeggini, E.; Zhang, F.; Jonsdottir, I.; Uitterlinden, A. G.; Felson, D. T.; Van Meurs, J. B.; Stefansson, K.; Ioannidis, J. P. A.; Spector, T. D. (2011)
      Objectives: Osteoarthritis (OA) is the most prevalent form of arthritis and accounts for substantial morbidity and disability, particularly in older people. It is characterised by changes in joint structure, including ...
    • A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip 

      Evangelou, E.; Kerkhof, H. J.; Styrkarsdottir, U.; Ntzani, E. E.; Bos, S. D.; Esko, T.; Evans, D. S.; Metrustry, S.; Panoutsopoulou, K.; Ramos, Y. F. M.; Thorleifsson, G.; Tsilidis, K. K.; Arden, N.; Aslam, N.; Bellamy, N.; Birrell, F.; Blanco, F. J.; Carr, A.; Chapman, K.; Day-Williams, A. G.; Deloukas, P.; Doherty, M.; Engstrom, G.; Helgadottir, H. T.; Hofman, A.; Ingvarsson, T.; Jonsson, H.; Keis, A.; Keurentjes, J. C.; Kloppenburg, M.; Lind, P. A.; McCaskie, A.; Martin, N. G.; Milani, L.; Montgomery, G. W.; Nelissen, Rghh; Nevitt, M. C.; Nilsson, P. M.; Ollier, W. E. R.; Parimi, N.; Rai, A.; Ralston, S. H.; Reed, M. R.; Riancho, J. A.; Rivadeneira, F.; Rodriguez-Fontenla, C.; Southam, L.; Thorsteinsdottir, U.; Tsezou, A.; Awallis, G.; Wilkinson, J. M.; Gonzalez, A.; Lane, N. E.; Lohmander, L. S.; Loughlin, J.; Metspalu, A.; Uitterlinden, A. G.; Jonsdottir, I.; Stefansson, K.; Slagboom, P. E.; Zeggini, E.; Meulenbelt, I.; Ioannidis, J. P. A.; Spector, T. D.; van Meurs, J. B. J.; Valdes, A. M.; arc, Ogen Consortium (2014)
      Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on ...